Most skincare is designed to improve how aging looks. But can it change what is happening inside the skin itself?

In this conversation, I sit down with Carolina Reis Oliveira, PhD, co-founder and CEO of OneSkin, to explore what actually drives skin aging at the cellular level. Carolina explains how senescent “zombie” cells, UV exposure, inflammation, hormonal changes and a weakened skin barrier affect how skin functions, not just how it looks.

Get OneSkin's new Rich Cream and the rest of the OS-01 line at:

oneskin.co/KAYLA with code KAYLA.

We break down the benefits and limitations of retinol, why chronic redness and flaking are not signs that a product is working better, and whether popular ingredients such as NAD+ precursors, methylene blue and GHK-Cu can penetrate the skin and remain stable. We also discuss collagen supplementation, red light therapy, hyperbaric oxygen, sauna, exercise, sun exposure and the relationship between skin-barrier health and systemic inflammation.

Carolina also shares the science behind OneSkin's OS-01 peptide and its new Face Rich Cream, including findings related to collagen, hyaluronic acid, elastin, filaggrin, hydration, firmness and fine lines.

In this conversation:

-Why many anti-aging products target visible symptoms rather than the biology of skin aging

-How senescent “zombie” cells contribute to inflammation and tissue decline

-How to use retinol without chronically damaging the skin barrier

-Why ingredient penetration, stability and formulation matter

-How skin-barrier dysfunction may affect inflammation throughout the body

-What collagen, red light, hyperbaric oxygen, sauna and exercise can do for the ski

- What OneSkin found when testing GHK-Cu copper peptides

-Why moisturizer alone may not solve age-related dryness

-How OS-01 is designed to target the underlying biology of skin aging

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https://kayla-barnes-lentz.circle.so/female-longevity-community

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Get up to $350 off at https://www.eightsleep.com/Kayla with code “KAYLA”

Support lean muscle and recovery with PerfectAmino essential amino acids: https://bodyhealth.com/products/perfectamino“Kayla20”

Connect with Kayla:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter:https://x.com/femalelongevity

Website:https://www.kaylabarnes.com/

Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054

Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Connect with Carolina Reis Oliveira:

Instagram: https://www.instagram.com/carolina.reis.phd/

LinkedIn: https://www.linkedin.com/in/carolina-reis-oliveira-a69b8a27/

X: https://x.com/Carol_roliveira

Learn more about OneSkin:

Shop OneSkin: https://oneskin.pxf.io/LKgxy0

Website: https://www.oneskin.co/

Instagram: https://www.instagram.com/oneskin.co/

LinkedIn: https://www.linkedin.com/company/oneskin/

Scientific publications: https://www.oneskin.co/pages/scientific-publications

#SkinLongevity #SkinHealth #HealthyAging #OneSkin #Retinol #SenescentCells #FemaleLongevity #KaylaBarnes

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